Use is approved when ALL of the following are met:
AAN-AHS, American Academy of Neurology-American Headache Society; HIT, Headache Impact Test; ICHD, International Classification of Headache Disorders; MHDs, monthly headache days; MIDAS, Migraine Disability Assessment.
‡Doctor of medicine, doctor of osteopathy, advanced practice provider (DDS [Doctor of Dental Surgery] or DMD [Doctor of Medicine in Dentistry or Doctor of Dental Medicine]).
§Patient can only meet criteria for C, D, or E.
||Not for use in women of childbearing potential who lack an appropriate method of birth control.
Drug Treatment—Acute and preventive
Acute and preventive treatment overview and options
Used to abort a migraine attack1,2
Eligible for many patients1
Possibility for overuse1-3
Reduces migraine attack frequency, duration,
Consider for patients with severe and/or frequent headaches that are not controlled with acute treatment1
Treatment choice factors include drug efficacy/safety, concomitant medications, comorbidities, and patient preference1,4-6
Learn more about MIGRAINE
NSAIDs: aspirin, diclofenac, ibuprofen, naproxen
Ergotamine and other forms of DHE
NSAIDs: ketoprofen, IV and IM ketorolac, flurbiprofen
Combinations: codeine/acetaminophen, tramadol/acetaminophen†
Antiemetics: prochlorperazine, promethazine, droperidol, chlorpromazine, metoclopramide
DHE, dihydroergotamine; IV, intravenous; IM, intramuscular; NSAID, nonsteroidal
*Use is not recommended.
†In migraine with aura.